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Autores
Categoria WoS
  • Biochemical Research Methods - Q2 - - 32/75
  • Chemistry, Analytical - Q2 - - 26/75
  • Biochemistry & Molecular Biology - Q3 - - 166/290
Area
  • Applications
  • Bioinformatics
Titulo: Two-Dimensional Gel Electrophoresis Image Registration using Block-Matching Techniques and Deformation Models
Tipo: revista internacional
Fecha: 6,2014
Revista: Analytical Biochemistry
JCR Journal; Impact Factor: 2.582
SCIMago SJR: 0.800
Volumen: Vol 454 (1)
Paginas: 53-59
ISSN: 0003-2697
Editorial: ACADEMIC PRESS INC ELSEVIER SCIENCE
doi: http://dx.doi.org/10.1016/j.ab.2014.02.027

Abstract:

Block-matching techniques have been widely used in the task of estimating displacement in medical images and they stand for the best approach in scenes with deformable structures such as tissues, fluids or gels. In this paper, a new iterative block-matching technique, based on successive deformation, search, fitting, filtering and interpolation stages is proposed to measure elastic displacements in two dimensional polyacrylamide gel electrophoresis images (2D-PAGE). The proposed technique uses different deformation models in the task of correlating proteins in real 2D electrophoresis gel images, obtaining an accuracy of 96.6% and improving the results obtained with other techniques. This technique stands for a general solution, being easy to adapt to different 2D deformable cases and providing an experimental reference for block-matching algorithms.

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